File server migration - changing drive letter

Hi,

I'm migrating a 2003 R2 file server to 2008 R2.

The old server has only one large C: partition.

On the new server, I want to separate the shared files from the OS by creating a D: partition for them.

If I do this, is it likely to cause any problems with the file shares (which include user profiles)?

Currently files are shared through DFS, which I intend to maintain, so I am optimistic that it will Just Work(TM), since those C:\ pathnames should be abstracted from the clients.

Please let me know if there's anything I need to watch out for!

Thanks
Dave